Information for Patients

Overview

What is the myTAIHEART Test?

The myTAIHEART test is a powerful non-invasive test that uses a small sample of blood to determine if a patient is at a low or increased risk of rejecting their heart transplant. myTAIHEART works by measuring the fraction of cell-free DNA (cfDNA) present in the bloodstream that is attributable to the transplanted heart. An elevated donor fraction (DF%) is associated with an increased risk of acute cellular rejection.

Talk to your doctor about whether myTAIHEART might be a useful part of your transplant care.

Why Choose myTAIHEART?

  • Can be used in patients as young as 2 months of age
  • Test as early as 7 days post-transplant
  • Non-invasive
  • Rapid results

How myTAIHEART Testing Works

Understanding cell-free DNA (cfDNA)

In all people, cfDNA is released into the bloodstream as a product of natural cell turnover. Injury by illness or trauma can also increase cfDNA levels. In heart transplant recipients, cfDNA is released by the cells of the transplanted heart in addition to the recipient’s native cells. These two types of cfDNA are genetically different, which enables the ratio of the two to be measured. The fraction of a transplant recipient’s total cfDNA that originates in the transplanted organ is known as the donor fraction (DF%). Above a certain threshold, elevated donor fractions indicate increased damage to the transplanted heart and an increased risk for acute cellular rejection.

Treatment for rejection and certain other conditions may interfere with measurement of the donor fraction, so a doctor’s clinical judgment is required to interpret myTAIHEARTresults.

The Testing Process

The myTAIHEART test requires a standard blood draw. Hospitals that offer myTAIHEART testing can draw your blood onsite, and will ship the sample overnight for processing at the TAI Diagnostics Clinical Laboratory. Results are reported back to the hospital within 2 business days of sample receipt.

Personal Health Information 🔒

TAI Diagnostics is committed to ensuring the safety and security of your Personal Health Information (PHI) and maintains HIPAA standard requirements.The Health Insurance Portability and Accountability Act (HIPAA) is designed to protect all forms of PHI, by defending the patients’ rights to have their health information kept private and preserving control of how their PHI data is used and when it is disclosed. The Privacy and Security Rules in HIPAA define the standards for protecting all forms of PHI and outlines specific Administrative and Technical Safeguards.

TAI Diagnostics closely adheres to these HIPAA standards in its system development and information processing methods to ensure that you and your family’s healthcare information is protected.

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